Infections in the survivors of out-of-hospital cardiac arrest in the first 7 days
Journal
Intensive Care Medicine
Journal Volume
31
Journal Issue
5
Pages
621-626
Date Issued
2005
Author(s)
Hsieh C.-C.
Hsu C.-Y.
Su C.-P.
Abstract
Objective: To evaluate the incidence, risk factors, foci, isolated organisms, and outcomes of infections in the survivors of out-of-hospital cardiac arrest (OHCA) within the first 7 days after resuscitation. Design and setting: Retrospective cohort study in the intensive care unit of a university hospital. Patients and participants: We enrolled 117 survivors of adult nontraumatic OHCA victims who survived more than 24 h between January 1999 and May 2004. We collected patients' demographics, the causes and initial electrocardiographic rhythm of cardiac arrest, and the process of cardiopulmonary resuscitation. The incidence, clinical presentations and outcomes of infections occurring in the first 7 days after resuscitation were evaluated. Variables were compared between the infected and noninfected patients. Measurements and results: Among our OHCA survivors asystole was the most common initial rhythm (66%). Eighty-three patients (71%) were found to have infection. Pneumonia was the most common infection (61%) followed by bacteremia (13%). Although the Gram-negative bacteria were responsible for most infections, the most commonly isolated organism was Staphylococcus aureus. The infection group had more patients with dementia and noncardiac causes of OHCA. The survival curves did not differ significantly between infection and noninfection groups. Conclusions: Infections were common in OHCA survivors during the first 7 days. The most common responsible organisms were Gram-negative bacteria, and the most commonly isolated organism was S. aureus. Infections in the early stage after return of spontaneous circulation did not change the hospital mortality and hospitalization duration. ? Springer-Verlag 2005.
SDGs
Other Subjects
antibiotic agent; abdominal infection; aged; article; asphyxia; asthma; asystole; bacteremia; bacterium isolation; brain stem infarction; catheter infection; chronic obstructive lung disease; clinical feature; cohort analysis; computer assisted tomography; controlled study; dementia; disease exacerbation; echography; electrocardiography; empyema; female; gastrointestinal hemorrhage; Gram negative bacterium; heart arrest; heart arrhythmia; heart injury; heart muscle ischemia; hospital discharge; hospital infection; hospitalization; human; hyperkalemia; infection risk; intensive care unit; major clinical study; male; medical assessment; mortality; pneumonia; resuscitation; retrospective study; skin infection; Staphylococcus aureus; subarachnoid hemorrhage; survival rate; thorax radiography; treatment outcome; university hospital; urinary tract infection; victim; wound infection; Aged; Bacteremia; Cardiopulmonary Resuscitation; Comorbidity; Female; Gram-Negative Bacterial Infections; Heart Arrest; Humans; Incidence; Infection; Intensive Care Units; Male; Pneumonia; Retrospective Studies; Risk Factors; Staphylococcal Infections; Taiwan
Type
journal article