Novel Urethane-acrylate Root Canal Sealer:Cytotoxicity and Antibacterial Effect
Date Issued
2011
Date
2011
Author(s)
Chen, Yen-Jung
Abstract
For sealing off of the root canal system after completely cleaning and shaping, the standard root canal filling is a combination of sealers with gutta-percha cone. The ideal root canal sealer needs good biocompatibility and antibacterial effect. Our research team has developed dual-cured urethane-acrylate (UA) sealer. Theses materials have good handling characteristics and bonding strength. For further research about the safety of urethane-acrylate sealer. The purposes of this study were to investigate the cytotoxicity and antibacterial effect of UA sealer.
The results showed the PC-based UA sealer and Apexit have lower cytotoxicity than PBA-based UA sealer and commercial products such as Endorez, AHplus and Tubliseal. In antibacterial effect test, AHplus has higher antibacterial effect and UA sealers have lower antibacterial effect than other commercial products. We conclude that the cytotoxicity and antibacterial effect have correlations, and the higher bactericide effect may also kill the normal cell. PC-based UA sealer with higher conversion rate and good biocompatibility has high potential for clinical use.
Subjects
root canal sealer
thermoplatic polyurethane
cytotoxicity
antibacterial effect
Type
thesis
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