Novel steroids from the soft coral Nephthea chabrolii
Resource
Tetrahedron 63 (3): 703-707
Journal
Tetrahedron
Journal Volume
63
Journal Issue
3
Pages
703-707
Date Issued
2007
Author(s)
Su, Jui-Hsin
Lin, Fang-Yee
Huang, Ho-Cheng
Wu, Yang-Chang
Hu, Wan-Ping
Hsu, Chi-Hsin
Sheu, Jyh-Horng
Abstract
Three new metabolites including two new steroids, chabrolosteroids A and B (1 and 2), and a novel spirosteroid chabrolosteroid C (3), were isolated from the organic extract of a Taiwanese soft coral Nephthea chabrolii. The structures of these metabolites were elucidated by extensive spectroscopic analysis and by comparison of the spectral data with those of related steroids. This is the first report of a steroid with a spiro-ring A, B system in natural products. ? 2006 Elsevier Ltd. All rights reserved.
Subjects
Chabrolosteroids; Nephthea chabrolii; Spirosteroid
Other Subjects
certonardosterol; chabrolosteroid A; chabrolosteroid B; chabrolosteroid C; steroid; article; breast carcinoma; cancer cell; cancer growth; comparative study; controlled study; coral; drug cytotoxicity; drug structure; human; human cell; liver cell carcinoma; lung carcinoma; metabolite; Nephthea chabrolii; priority journal; spectroscopy; Alcyonacea; Nephthea
Type
journal article
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