Antidepressant-like effects of water extract of Cordyceps militaris (Linn.) Link by modulation of ROCK2/PTEN/Akt signaling in an unpredictable chronic mild stress-induced animal model
Journal
Journal of Ethnopharmacology
Journal Volume
276
Date Issued
2021-08-10
Author(s)
Lin, Yu-En
Chen, Yi-Chun
Huang, Yun-Ju
Panyod, Suraphan
Liu, Wei-Ting
Yang, Shu-Hui
Lu, Yun-Sheng
Chen, Mei-Hsing
Abstract
Cordyceps militaris (Linn.) Link (CM) is a medicinal mushroom traditionally used in tonics for treating several neurological disorders, including epilepsy and anxiety, in Asia. Reports have shown that CM has anti-inflammatory and anti-oxidative effects and may be beneficial for depression management.
Subjects
Cordyceps militaris; Depression; Neurodegeneration; ROCK2/PTEN/Akt pathway; Unpredictable chronic mild stress
Publisher
ELSEVIER IRELAND LTD
Type
journal article