Fatal acute-on-chronic liver failure in amiodarone-related steatohepatitis: a case report
Journal
BMC gastroenterology
Journal Volume
21
Journal Issue
1
Date Issued
2021-02-02
Author(s)
Abstract
Amiodarone is an antiarrhythmic drug that has been recognized to induce hepatotoxicity. We report a case of acute-on-chronic liver failure (ACLF) in a patient who was receiving amiodarone for more than 2 years. The patient developed cirrhosis and suppurative microabscesses of the liver and died of progressive liver failure.
Subjects
Acute-on-chronic liver failure; Amiodarone; Case report; Microabscess; Steatohepatitis
SDGs
Other Subjects
alanine aminotransferase; albumin; amiodarone; aspartate aminotransferase; bilirubin; C reactive protein; fluorodeoxyglucose f 18; amiodarone; antiarrhythmic agent; abdominal distension; abdominal tenderness; acute on chronic liver failure; aged; alanine aminotransferase level; albumin blood level; Article; ascites; aspartate aminotransferase blood level; bilirubin blood level; blood clotting disorder; case report; chronic disease; clinical article; computer assisted tomography; coronary artery bypass graft; coronary artery disease; deterioration; diabetes mellitus; disease duration; epigastric pain; eye disease; female; granulation tissue; hepatomegaly; histiocyte; hospital admission; human; human tissue; hyperbilirubinemia; hyperlipidemia; international normalized ratio; kidney failure; laboratory test; leukocytosis; liver biopsy; liver parenchyma; Model For End Stage Liver Disease Score; nonalcoholic fatty liver; nonalcoholic steatohepatitis; outcome assessment; periportal edema; positron emission tomography; prothrombin time; pyuria; tachycardia; vomiting; complication; liver cirrhosis; toxic hepatitis; Acute-On-Chronic Liver Failure; Aged; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Cirrhosis
Publisher
BMC
Type
journal article