Metasurface-Based Abrupt Autofocusing Beam for Biomedical Applications
Journal
Small methods
Journal Volume
6
Journal Issue
4
Date Issued
2022-04
Author(s)
Tseng, Ming Lun
Vyas, Sunil
Kuo, Hsin Yu
Chu, Cheng Hung
Chen, Mu Ku
Su, Vin-Cent
Shi, Xu
Misawa, Hiroaki
Tsai, Din Ping
Abstract
Manipulation and precise delivery of optical energies in the regions of interest within specimens require different strategies. Hence, proper control of input beam parameters is a prerequisite. One of the prominent methods is metasurface optics, capable of crafting properties of light at nanoscales. Here, the generation of an abrupt autofocusing (AAF) beam by a nanophotonic metasurface for biomedical applications is demonstrated. Fluorescence guided laser microprofiling of mouse cardiac samples is experimentally investigated, using the AAF beam to deliver optical energy selectively to specific locations. In addition, photocoagulation of ex vivo swine skin tissue is performed and observed through optical coherence tomography. The results show great potentials for integrating metasurface optics to realize miniature laser surgery instruments for wide applications in biomedicine.
Subjects
abrupt autofocusing beam; laser surgery; metasurfaces
SDGs
Other Subjects
Medical applications; Optical tomography; Abrupt autofocusing beam; Auto-focusing; Beam parameter; Biomedical applications; Metasurface; Nano scale; Optical energy; Property; Region-of-interest; Regions of interest; Laser surgery; animal experiment; animal tissue; article; biomedicine; controlled study; ex vivo study; fluorescence; heart; laser coagulation; laser surgery; male; mouse; nonhuman; optical coherence tomography; optics; pig; skin
Publisher
WILEY-V C H VERLAG GMBH
Type
journal article