The Anti-Obesity and Anti-Inflammatory Capabilities of Pterostilbene and its Colonic Metabolite Pinostilbene Protect against Tight Junction Disruption from Western Diet Feeding
Journal
Molecular nutrition & food research
Journal Volume
66
Journal Issue
16
Date Issued
2022-08
Author(s)
Abstract
Tight junctions (TJs) are a member of the intestinal epithelium barrier that provides the first line of protection against external factors. Anti-obesity and protective effects of pterostilbene (PSB) on TJs have previously been reported, but the effect of its colonic metabolite, pinostilbene (PIN), is less understood.
Subjects
colonic tight junctions; macrophage polarization; pinostilbene; pterostilbene; western diet
SDGs
Publisher
WILEY
Type
journal article