Correlation between microRNA-34a levels and lens opacity severity in age-related cataracts
Journal
Eye (London, England)
Journal Volume
27
Journal Issue
7
Date Issued
2013-07
Author(s)
Chien, K-H
Chen, S-J
Liu J.-H.
Chang, H-M
Liang, C-M
Chen, J-T
Lin, T-J
Chiou, S-H
Peng, C-H
Abstract
MicroRNA 34a (miR-34a) is involved in regulating tissue senescence. However, the role of miR-34a in age-related cataracts is unclear. In this study, we evaluated the correlations among the severity of lens opacity, patient age, and miR-34a expression level in the lens epithelium of age-related cataracts for clarifying the role of miR-34a in the lens senescence.
Subjects
Aging | Cataract | MicroRNA | Senescence
SDGs
Type
journal article