Mycobacterium kansasii infection preseting as cellulitis in a patient with systemic lupus erythematosus
Journal
Journal of the Formosan Medical Association
Journal Volume
101
Journal Issue
8
Pages
581-8584
Date Issued
2002
Author(s)
Abstract
The prevalence of mycobacterial infection has increased in recent years, especially in patients immunocompromised due to autoimmune disease, malignancy and AIDS. Mycobacterium kansasii infection most commonly presents as tuberculosis-like pulmonary disease. We report the case of a 38-year-old woman with systemic lupus erythematosus (SLE) who developed cellulitis over the left lower leg and had poor response to antibiotics. Two months before this admission, she had sustained a small wound over the right pretibial area and had noticed erythematous swelling after swimming at the beach. Pathologic examination of biopsied tissue showed acid-fast bacilli, and culture yielded M. kansasii. The cellulitis improved gradually during treatment with antimycobacterial agents for 1 year. This case emphasizes the possibility that cutaneous M. kansasii infection may occur in an immunocompromised patient and that exposure to contaminated water is a possible source. With early diagnosis, the response to an antimycobacterial multidrug regimen is usually satisfactory.
SDGs
Other Subjects
amoxicillin plus clavulanic acid; amphotericin B; ampicillin; antibiotic agent; antimycobacterial agent; azathioprine; cefixime; ceftazidime; ciprofloxacin; clarithromycin; corticosteroid; dicloxacillin; doxycycline; erythromycin; ethambutol; hydroxychloroquine; immunosuppressive agent; indapamide; isoniazid; macrolide; meloxicam; oxacillin; prednisolone; quinoline derived antiinfective agent; rifampicin; streptomycin; vancomycin; acid fast bacterium; acquired immune deficiency syndrome; adult; anamnesis; antibiotic therapy; article; autoimmune disease; bacterium culture; biopsy; cancer; case report; cellulitis; drug response; early diagnosis; environmental exposure; erythema; female; histopathology; human; immune deficiency; leg disease; lung tuberculosis; mycobacteriosis; Mycobacterium kansasii; prevalence; skin infection; swimming; systemic lupus erythematosus; treatment outcome; water contamination; wound infection; Adult; Cellulitis; Female; Humans; Lupus Erythematosus, Systemic; Mycobacterium Infections, Atypical; Mycobacterium kansasii; Skin; Water Microbiology
Type
journal article