Study of the Kinetics for Depolymerization of Chitosan by Using Acetic Acid
Date Issued
2007
Date
2007
Author(s)
Lin, Yu-Dung
DOI
en-US
Abstract
Chitosan is a novel medical material recently. Our lab is focus on controlling the molecular weight of chitosan. It was found that the chitosan with molecular weight at ten-thousand grades has some special characteristics, like antibiotic, faster degredational rate, etc... So it was important to control the molecular weight of chitosan. There are some methods to control the molecular weight of chitosan like supersonic waving,, enzyme methods, and acid-alkali methods, etc... In this paper, acid-handling method was chosen methods based on cost and mass-production. First we use different concentration of acetate to handle chitosan. Then we use acetone to extract the chitosan. We change the reaction time, the concentration of acetic acid, and fix other factors. Then we discuss how the time and the concentration of acetate affect the molecular weight of chitosan. From the view of kinetics, the depolymerization of chitosan is a zero-order reaction for the reactant (chitosan). The depolymerization of chitosan is a first-order reaction for the catalyst (acetic acid). TGA can prove the depolymerization of chitosan was happening and the solubility of chitosan is whole soluble for water if the molecular weight of chitosan is below 100,000.
Subjects
幾丁聚醣
分子量
降解
醋酸
chitosan
molecular weight
degradation
depolymerization
acetic acid
Type
thesis
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