Chapter 13 Entensions of Mendelian Genetic Analysis

1. Relationship between phenotype and gene can be studied through mutants identified by phenotype distinct from wild type.
2. Complementation test (cis-trans test) determines whether independently isolated mutations for the same phenotype are in the same or different genes by crossing two mutants (Figure 13.1).
a. If mutations are in different genes, phenotype will be wild type (complementation).
b. If mutations are in the same gene, phenotype will be mutant (no complementation).