The Hemodynamic Study of Left Ventricular Assist Device
Date Issued
2004
Date
2004
Author(s)
Chen, Chi-Fu
DOI
zh-TW
Abstract
A revised Tai-Ta centrifugal impeller pump was designed to study the hemodynamic interaction of left ventricular assist device (LVAD) with the cardiovascular system in a canine model for pediatrics. After correcting the time delay between flow wave and pressure wave, we could realize the function of heart stroke. The LVAD outflow appeared to be pulsatile that matched with the cardiac cycle.
The efficiency of pumping for LVAD inlet inserted directly through apex of heart was better than that through atrium. When the LVAD was operated at a higher rotational speed, the ABP, POP, pump flow, and the cardiac output flow increased. However, the fluctuating amplitudes of ABP, POP, and pump flow decreased prominently. When the share flow of LVAD was more than 70%, the flow of coronary artery decreased slightly, but the flow of common carotid artery increased slightly. This study showed that the centrifugal impeller pump could be used as an assist device when the cardiac function was impeded.
When the canine suffered heart failure,the LVAD could support the function of circulation to avoid the other organ failure. The myocardiac function could be recovered by pulsatile stimulus of LVAD.The LVAD could be used as an aid apparatus of heart failure in urgency.
Subjects
脈動流場
心臟衰竭
血液動力學
犬隻模型
離心式葉輪幫浦
左心室輔助器
pulsatile flow
canine model
left ventricular assist device
hemodynamics
centrifugal impeller pump
heart failure
Type
thesis
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