Confocal viviperception of a transparent medaka fish (Otyzias latipes) using functionalized mesoporous silica nanoparticles (MSNs)
Journal
Chemistry Letters
Journal Volume
40
Journal Volume
40
Journal Issue
5
Journal Issue
5
Pages
533-535
Start Page
533
End Page
535
ISSN
13480715
Date Issued
2011
Author(s)
Abstract
With utilization of a transparent medaka fish {Oryzias latipes) and fluorescent confocal microscopy, essential knowledge about biodistribution offluorescein isothiocyanate {FITC)- functionalized mesoporous silica nanoparticles {MSNs) withina living organism becomes accessiblewithout tissue dissection. Data evidences bioaccumulation of FITC-MSNs in liver, gill, and intestine after one month's aqueous exposure. FITC-MSNs were mainly retained in liver for at least a week even after those in intestine had been excreted out.
SDGs
Type
journal article