Planning mass eradication of Helicobacter pylori infection for indigenous Taiwanese peoples to reduce gastric cancer
Journal
Journal of Gastroenterology and Hepatology (Australia)
Journal Volume
35
Journal Issue
4
Pages
609-616
Date Issued
2020
Author(s)
Bair M.-J.
Chuang S.-L.
Lei W.-Y.
Chen C.-L.
Tian H.-W.
Su W.W.-Y.
Lin C.-C.
Chung Lo Y.-T.
Jou Y.-Y.
Wu C.-Y.
Chia S.-L.
Chu C.-H.
Wang Y.-W.
Abstract
Background and Aim: The aim of this study is to identify gastric cancer burden in Indigenous Taiwanese peoples and conduct a project to evaluate how to reduce the disparities most effectively in Indigenous communities. Methods: First, we quantified the health disparities in gastric cancer in Indigenous peoples using data from the cancer registries during the period of 2006–2014. Second, we identified parameters that might be associated with Helicobacter pylori infection or help identify a good eradication strategy. Results: Gastric cancer incidence (24.4 vs 12.3 per 100?000 person-years) and mortality rates (15.8 vs 6.8 per 100?000 person-years) were higher in Indigenous than in non-Indigenous, with 2.19-fold (95% confidence interval [CI]: 2.06–2.33) and 2.47-fold (2.28–2.67) increased risk, respectively. In Indigenous communities, H.?pylori infection was more prevalent in Indigenous than in non-Indigenous (59.4% vs 31.5%, P?
SDGs
Other Subjects
amoxicillin; clarithromycin; lansoprazole; levofloxacin; urea c 13; clarithromycin; Article; Austronesian people; betel nut chewing; cancer incidence; cancer mortality; cancer prevention; cancer registry; controlled study; disease eradication; female; health disparity; Helicobacter infection; human; indigenous people; infection rate; limit of quantitation; male; mastication; mortality rate; multiple cancer; priority journal; retreatment; smoking; stomach cancer; Taiwanese; treatment failure; tumor volume; urea breath test; adverse event; Areca; combination drug therapy; complication; cost of illness; gastritis; health care disparity; Helicobacter infection; Helicobacter pylori; incidence; microbiology; mortality; prevalence; risk factor; stomach tumor; Taiwan; Areca; Clarithromycin; Cost of Illness; Drug Therapy, Combination; Gastritis; Healthcare Disparities; Helicobacter Infections; Helicobacter pylori; Incidence; Indigenous Peoples; Prevalence; Risk Factors; Smoking; Stomach Neoplasms; Taiwan
Publisher
Blackwell Publishing
Type
journal article