麻醉模型之建立
Date Issued
2001-07-31
Date
2001-07-31
Author(s)
DOI
902213E002060
Abstract
An automatic system was designed for
the control and mornitoring of the anesthetic
depth of the rat. This window-based system
is capable of measuring blood pressure (BP)
and electroencephagram (EEG), and
controlling the drug delivery by an infusion
pump. To understand mechanisms involved
in anesthesia, the changes of BP, the effects
of body weight of the experiment animals,
and the concentration of the anesthetic agent
during an experiment were recorded.
Later analysis shows that the BP decays as
the depth of anesthesia increases. The time
needed for a rat to die due to overdose of
anesthesia is proportionally increased as the
rat's body weight increases in an exponential
manner. On the other hand, such a time is
inversely proportional to the concentration of
the anesthetic drug. It is suggested that a
conbined curve template may be an adequate
index for the monitoring of anesthetic level.
Subjects
blood pressure
anesthesia
rat
automatic control
Publisher
臺北市：國立臺灣大學醫學工程學研究所
Type
report
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