Dicopper complexes catalyzed coupling/cyclization of 2-bromobenzoic acids with amidines leading to quinazolinones
Journal
Applied Organometallic Chemistry
Journal Volume
28
Journal Issue
9
Pages
661-665
Date Issued
2014
Author(s)
Abstract
Dicopper(I) complexes {Cu2(bpnp)(CH3CN) 4}(PF6)2] (2), [{Cu2(bpnp)(CH 3CN)4}(BAr4F)2] (3) and [Cu2(bpnp)Cl2] (4) were prepared from the complexation of [Cu(CH3CN)4](PF6) with 2,7-bis(2-pyridyl)-1,8- naphthyridine (bpnp) followed by anion metathesis and treatment of chloride sequentially. The X-ray structural analysis of 4 indicates the molecule to have a twofold axis passing through the Cu2Cl2 core, which has the shape of a butterfly, and that the Cu atom is tetrahedrally coordinated with in a Cl2N2 donor set. In preliminary experiments 2 was found to be an effective catalyst in the coupling/cyclization of 2-bromobenzoic acids with amidines, providing the corresponding quinazolinones in good yields. Copyright © 2014 John Wiley & Sons, Ltd.
Type
journal article