Investigation of a scanned cylindrical ultrasound system for breast hyperthermia
Journal
Physics in Medicine and Biology
Journal Volume
51
Journal Issue
3
Pages
539-555
Date Issued
2006
Author(s)
Abstract
This paper investigates the feasibility of a scanned cylindrical ultrasound system for producing uniform heating from the central to the superficial portions of the breast or localized heating within the breast at a specific location. The proposed system consists of plane ultrasound transducer(s) mounted on a scanned cylindrical support. The breast was immersed in water and surrounded by this system during the treatment. The control parameters considered are the size of the transducer, the ultrasound frequency, the scan angle and the shifting distance between the axes of the breast and the system. Three-dimensional acoustical and thermal models were used to calculate the temperature distribution. Non-perfused phantom experiments were performed to verify the simulation results. Simulation results indicate that high frequency ultrasound could be used for the superficial heating, and the scan angle of the transducer could be varied to obtain an appropriate high temperature region to cover the desired treatment region. Low frequency ultrasound could be used for deep heating and the high temperature region could be moved by shifting the system. In addition, a combination of low and high frequency ultrasound could result in a portion treatment from the central to the superficial breast or an entire breast treatment. Good agreement was obtained between non-perfused experiments and simulation results. The findings of this study can be used to determine the effects of the control parameters of this system, as well as to select the optimal parameters for a specific treatment. © 2006 IOP Publishing Ltd.
SDGs
Other Subjects
Computer simulation; Control theory; Mathematical models; Scanning; Temperature distribution; Ultrasonic equipment; Ultrasonic waves; Ultrasonics; Water; Breast hyperthermia; Localized heating; Plane ultrasound transducer; Three-dimensional acoustical model; Biological organs; article; breast; heating; high temperature; hyperthermia; mathematical analysis; mathematical computing; priority journal; simulation; temperature; ultrasound; ultrasound transducer; water immersion; Acoustics; Body Temperature; Breast; Computer Simulation; Fever; Heat; Humans; Hyperthermia, Induced; Imaging, Three-Dimensional; Models, Statistical; Perfusion; Phantoms, Imaging; Reproducibility of Results; Temperature; Time Factors; Ultrasonic Therapy; Ultrasonics
Type
journal article