Necrotising fasciitis: Clinical features in patients with liver cirrhosis
Journal
British Journal of Plastic Surgery
Journal Volume
58
Journal Issue
5
Pages
702-707
Date Issued
2005
Author(s)
Abstract
Necrotising fasciitis is a fulminant and life-threatening infection. It is associated with a high mortality rate and is often seen in the aged and immunocompromised patients. Liver cirrhosis is regarded as a risk factor of necrotising fasciitis. From January 1995 to December 2003, 17 cirrhotic patients who had been admitted to our hospital for necrotising fasciitis were identified. The infection all developed in the lower extremities. Only six patients survived, and the overall case fatality rate was 64.7%. The cases were divided into two groups: survivors and nonsurvivors. Comparisons were made on age, gender, presenting symptoms, underlying medical diseases, laboratory data and clinical course. Underlying diabetes mellitus and grade C liver cirrhosis were the only statistically significant factors that led to poor prognosis (p<0.05). ? 2005 The British Association of Plastic Surgeons. Published by Elsevier Ltd. All rights reserved.
SDGs
Other Subjects
adult; age distribution; aged; article; clinical article; clinical feature; controlled study; diabetes mellitus; disease course; fatality; female; human; immune deficiency; leg; liver cirrhosis; male; mortality; necrotizing fasciitis; priority journal; prognosis; risk factor; sex difference; statistical significance; survival; treatment outcome; Adult; Aged; Aged, 80 and over; Diabetes Complications; Fasciitis, Necrotizing; Female; Humans; Leg; Liver Cirrhosis; Male; Middle Aged; Prognosis; Retrospective Studies; Risk Factors
Type
journal article