Structure and anti-acetylcholinesterase activity of 4α- (hydroxymethyl)-4α-demethylterritrem B
Journal
Journal of Natural Products
Journal Volume
60
Journal Issue
8
Pages
842-843
Date Issued
1997
Author(s)
Abstract
The structure of a metabolite produced on incubation of territrem B (1) with rat liver microsomes has been established to be 4 alpha-(hydroxymethyl)-4 alpha-demethylterritrem B (5). Compound 5 was a potent inhibitor of electric eel acetylcholinesterase (AChE) (E.C. 3.1.1.7).
SDGs
Type
journal article