A Study on Hyperthyroidism Treatment Patterns in Taiwan
Date Issued
2009
Date
2009
Author(s)
Lee, Tai-Chi
Abstract
This study was intended to explore the treatment and follow-up patterns of hyperthyroidism in Taiwan and compared with guideline standards.Claims data of hyperthyroidism cases of the National Health Research Institute were collected as the data base for analysis during the period 1997 to 2004. The washout duration of new incident treated as hyperthyroidism was 3 years. The subjects who had received anti-thyroid drugs or radioiodine or thyroid operation with the principle diagnosis of hyperthyroidism as the initial treatment of hyperthyroidism between 2000 and 2004 were included in our research. In total, there were 1151 new incident treated hyperthyroidism. The annual incidence was 1.2‰ to 1.4‰ from 2000 to 2004. The female incidence was 2.02‰ and male incidence was 0.58‰. Respectively sex ratio was 3.5 : 1. The peak age was 51 to 60 y/o in female and 31-40 y/o and 71-80 y/o in male. Hyperthyroidism was not a rare disease in aged population. There were 949 subjects (82%) received antithyroid drug as the first line therapy;202 subjects (17.5%) received thyroid operation as the first line therapy; only 6 subjects (0.5%) received radioiodine as the first line therapy. The mean treatment duration with antithyroid drug was 286.5 days in female and 288.5 days in male. Relapse occurred in 42.6% patients during the follow-up period after drug withdraw. Remission analysis revealed that the mean relapse time was 2.6 years and median relapse time was 2.28 years. Compared with the internation treatment guideline , appropriate thyroid function monitoring after medication was found in 48.2% patients and appropriate antithyroid drug treatment duration was found only in 15.7% patients.he factors associated with appropriate thyroid function follow-up were patient’s age、geographic area and hospital types. The related variables to appropriate medication were patient’s age and proper thyroid function monitor.
Subjects
National Health Insurance
Hyperthyroidism
Treatment Patterns
Epidemiology
Health Care Utilization
Taiwan
Type
thesis
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