Herpes tester oticus treated with acyclovir and prednisolone: Clinical manifestations and analysis of prognostic factors
Journal
Clinical Otolaryngology and Allied Sciences
Journal Volume
25
Journal Issue
2
Pages
139-142
Date Issued
2000
Author(s)
Abstract
Herpes zoster oticus is a cranial polyneuropathy with facial nerve involvement as its main feature. The prognosis of the facial palsy is usually poor. Thirty patients with herpes zoster oticus suffering from facial palsy were admitted for parenteral acyclovir and oral prednisolone. Multiple regression analysis of improvement of facial palsy showed three significant covariates: age, multiple nerve palsies, and the initial grading of the palsy. The recovery of the facial palsy treated with acyclovir and prednisolone was good, and possibility of a good outcome was greater when the initial grade of the palsy was higher. Multiple nerve palsies and age had negative effects on the improvement.
Subjects
Acyclovir; Herpes zoster oticus; Prednisolone; Prognostic factors
SDGs
Other Subjects
aciclovir; prednisolone; aciclovir; antiinflammatory agent; antivirus agent; prednisolone; adult; age; aged; article; clinical article; disease severity; facial nerve paralysis; female; herpes zoster oticus; human; male; multiple regression; priority journal; adolescent; animal; classification; drug combination; facial nerve paralysis; herpes zoster oticus; hospitalization; middle aged; prognosis; rat; retrospective study; Acyclovir; Adolescent; Adult; Animals; Anti-Inflammatory Agents; Antiviral Agents; Drug Therapy, Combination; Facial Paralysis; Herpes Zoster Oticus; Humans; Middle Aged; Prednisolone; Prognosis; Rats; Retrospective Studies; Severity of Illness Index
Type
journal article