Consensus statement on antimicrobial therapy of intra-abdominal infections in Asia
Journal
International Journal of Antimicrobial Agents
Journal Volume
30
Journal Issue
2
Pages
129-133
Date Issued
2007
Author(s)
Hawkey P.M.
Abstract
The selection of antimicrobial agents in the 2006 Guidelines (consensus statement) on Empiric Therapy for Complicated Intra-Abdominal Infections (IAIs) in Asia was based on resistance and epidemiological data from the Asian region. In these 2006 guidelines, single agent therapy using the β-lactam/β-lactamase inhibitors ampicillin/sulbactam or cefoperazone-sulbactam is recommended for mild-to-moderate cases, while piperacillin-tazobactam is recommended for high-severity cases. When using carbapenems, ertapenem is recommended for mild-to-moderate cases, while imipenem and meropenem are recommended for high-severity cases. For combination regimes, two types of agents are recommended: cephalosporin-based and monobactam-based. For mild-to-moderate cases, a third generation cephalosporin plus metronidazole is recommended. For high-severity cases, a third or fourth generation cephalosporin plus metronidazole ± amikacin is recommended. For the monobactam-based regimen, aztreonam plus metronidazole is recommended for high-severity cases only. ? 2007 Elsevier B.V. and the International Society of Chemotherapy.
SDGs
Other Subjects
amikacin; aztreonam; beta lactam antibiotic; beta lactamase inhibitor; carbapenem; cefepime; cefoxitin; ceftazidime; ceftriaxone; cephalosporin derivative; chloramphenicol; ciprofloxacin; clindamycin; ertapenem; flomoxef; imipenem; levofloxacin; meropenem; metronidazole; monobactam; piperacillin plus tazobactam; sulperazon; sultamicillin; timentin; tobramycin; abdominal infection; antibiotic resistance; antibiotic sensitivity; article; Asia; bacterium isolate; consensus; disease severity; drug effect; drug efficacy; drug indication; drug use; Gram negative bacterium; Gram positive bacterium; human; nonhuman; practice guideline; priority journal; Abdomen; Anti-Infective Agents; Asia; Bacterial Infections; beta-Lactamases; Consensus; Drug Resistance, Bacterial; Drug Therapy, Combination; Enterobacteriaceae; Enterobacteriaceae Infections; Fluoroquinolones; Humans; Penicillanic Acid; Piperacillin; Practice Guidelines
Type
journal article