Efficacy of Liver-Directed Combined Radiotherapy in Locally Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis
Journal
Cancers
Journal Volume
15
Journal Issue
12
Date Issued
2023-06-13
Author(s)
Kim, Jina
Nam, Taek-Keun
Kim, Jin Hee
Jang, Byoung Kuk
Huang, Wen-Yen
Aikata, Hiroshi
Kim, Myungsoo
Kwon, Jung Hyun
Yue, Jinbo
Lee, Victor Ho Fun
Zeng, Zhaochong
Seong, Jinsil
Abstract
Although systemic treatment is the mainstay for advanced hepatocellular carcinoma (HCC), numerous studies have highlighted the added value of local treatment. This study aimed to investigate the clinical efficacy of liver-directed combined radiotherapy (LD combined RT) compared with that of sorafenib, a recommended treatment until recently for locally advanced HCC presenting portal vein tumor thrombosis (PVTT), using a multinational patient cohort.
Subjects
hepatocellular carcinoma; portal vein tumor thrombosis; prognostic factors; radiotherapy; sorafenib
SDGs
Type
journal article