Department of Engineering Science & Ocean Engineering
Date Issued
2007
Date
2007
Author(s)
Hsieh, Chang-Hung
DOI
zh-TW
Abstract
Hepatocellular carcinoma is a group of diseases in which cells are aggressive.
Because of the advantage of focused ultrasound surgery(FUS), which is a non-invasive
system, the focused ultrasound surgery becomes one of the ideal ways to kill the tumor.
Most of the geometrical models considered in the previous studies were regular. In this
study, the liver model containing a liver, blood vessel(artery), and a liver tumor, which
is closed to the blood vessels, and considered. Since the presence of blood perfusion can
limit the ability of elevating the temperature owing to convective heat transport, the
reduction of lesion area is investigated.
Tissue absorbing coefficients play an important role in raising tumor temperature.
The range of the absorbing coefficients (liver tumor) is 0.0529(nepes/cm/MHz) to
0.1473(nepes/cm/MHz). After exposing to a high intensity focused ultrasound(HIHU)
for 12sec, the highest temperature with large absorbing coefficient can reach 83°C , and
the highest temperature with a lower absorbing coefficient is predicted to be 62°C . It is
difficult to get the coefficients in human body. Prior to the simulation, to acquire the
absorbing coefficients is essential to predict good quality solution.
Subjects
肝癌
超音波熱治療
血液灌流
吸收參
數
三維
Hepatocellular carcinoma
Focused Ultrasound Surgery(FUS)
High Intensity
SDGs
Type
thesis
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