Modulation of the anticancer activities of paclitaxel by Cremophor micelles
Journal
International Journal of Pharmaceutics
Journal Volume
603
Pages
120699
Date Issued
2021
Author(s)
Chiang J.-L.
YA-WUN YANG
Abstract
The objective of this study was to determine the effect of Cremophor (CrEL) on the antineoplastic effect induced by paclitaxel (PTX). Fluorescence spectroscopy, employing pyrene as a probe, was used to determine the critical micelle concentration (CMC) of
Subjects
Cell cycle; Cremophor; Micelle; Paclitaxel; Polyploidy
SDGs
Other Subjects
alpha tubulin; cremophor; Ki 67 antigen; lipocortin 5; paclitaxel; propidium iodide; pyrene; antineoplastic agent; cremophor; macrogol; paclitaxel; animal cell; animal experiment; animal model; animal tissue; antineoplastic activity; Article; bone marrow
Type
journal article