Factor analysis of nanowire biosensor and its challenges for future application in market
Date Issued
2016
Date
2016
Author(s)
Cheng, Hua
Abstract
As technologies continuously developed, point-of-care testing (POCT) has become an important research direction. Among different developed POCT technologies, nanowire field effect transistor (NW-FET) is one of promising technologies featuring high sensitivity and rapid diagnosis. On the other hand, acute coronary syndrome (ACS) has become a serious cardiovascular disease following developments of human societies. As a consequence, it is intriguing to have a detail market analysis for using NW-FET POCT technology in ACS diagnosis. At the same time, this analysis also shows important issues for the development of NW-FET based POCT technologies. Based on previous research results, commercial-available CMOS processes can be used to implement poly-silicon NW-FET for cardiovascular biomarker diagnosis. Since the market analysis shows several important issues for the development of NW-FET based PCT technologies, in this work, these issues, such as different doping concentration, oxide thickness, and channel depth, are addressed and verified in simulations. In addition, experiments are also employed to examine the fabricated devices. Based on this work, some of the major obstacles of CMOS-based NW-FET biosensors for POCT applications can be raised and evaluated.
Subjects
nanowire
biosensor
cardiac enzyme
SDGs
Type
thesis
File(s)![Thumbnail Image]()
Loading...
Name
ntu-105-R02945007-1.pdf
Size
23.32 KB
Format
Adobe PDF
Checksum
(MD5):312a9aee22cc6a284cd2b7acbac94807