A Study of Arterial System Terminal based on Radial Resonance Theory: Loop and Microcirculation Structure
Date Issued
2006
Date
2006
Author(s)
Pin-tsun,Chao
DOI
zh-TW
Abstract
Abstract
The circulatory system is the most important for maintaining life. Modern western medicine treats heart as a pump, and considers heart pumps blood into artery. However, it is hard to believe that heart can overcome the high resistance of the arterial system with only 1.7Watt output power. Besides, there is no efficient solution on nowadays prevailing cardiovascular disease.
Since the potential energy on aorta in vivo is more than 90%, which is much more than the axial kinetic energy, radial resonance theory(RRT), proposed by Dr. Wang and Dr. Lin, infers that circulatory system deliver energy by pressure, not flow. In one pressure-transmission system, the terminal condition of system will affect the stability of system. Here we will discuss two structures of arterial terminals: loop structure and microcirculation. We will discuss the meaning and function of these two structures based on RRT.
The terminal of arterial system is formed by net-like microcirculatory bed, and microcirculatory function and anatomy has been studied for long time. Here we discuss the microcirculation function based on RRT, and try to verify if microcirculation as strong reflection site, which is proposed by reflection theory.
Using the heartbeat as a trigger, we investigated whether the relation between pressure and flux can be used to discriminate different microcirculatory conditions. We propose the three pulsatile indices for evaluating the microcirculation condition from the normalized pressure and flux segment with a synchronized-averaging method. The abdominal aortic blood pressure and renal cortex flux (RCF) signals were measured in spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY). The mean value of the RCF did not differ between SHR and WKY. However, both PDT and FRT were longer in SHR than in WKY. We propose that a new dimension for comparing the LDF signals, which the results from the present study show, can be used to discriminate RCF signals that cannot be discriminated using traditional methods.
Researches for loop structure nowadays are mostly anatomical description and treat loop as useless in hemodynamics. However, based on the availability on body, we think it must contain more specific function, such as reduction of reflection or maintain of main frequency. Tube experiments and animal experiments were conducted to prove the functions mentioned. It seems that the loop structure is the best design after long evolution.
Through the vision of RRT, we not only proposed one new signal analysis method to analyze microcirculation, but also find the importance of loop structure in arterial system. In the future, we believe that with the help of this theory, we can provide more efficient treatment and evaluation method for clinical use.
Subjects
血液流體力學
環狀結構
微循環
雷射都卜勒
徑向共振理論
hemodynamics
loop structure
microcirculation
laser Doppler
radial resonance theory
SDGs
Type
thesis
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