MR findings of intrathecal chemotherapy-related myelopathy in two cases: Mimicker of subacute combined degeneration
Journal
Journal of Neuroimaging
Journal Volume
17
Journal Issue
2
Pages
184-187
Date Issued
2007
Author(s)
Abstract
We report the findings of spinal magnetic resonance imaging (MRI) in 2 patients who had undergone intrathecal chemotherapy and presented with the subacute onset of ascending numbness and weakness. MRI revealed a symmetric hyperintensity at the posterior columns of the spinal cord from the lower cervical region down to the conus medullaris level on T2-weighted images, and no abnormal enhancement. The imaging findings are similar to those seen in subacute combined degeneration (SCD), but the serum vitamin B12 levels were normal in these 2 cases. ? 2007 by the American Society of Neuroimaging.
SDGs
Other Subjects
cyanocobalamin; cytarabine; folic acid; hydrocortisone; methotrexate; adult; article; B cell lymphoma; blast cell; cancer radiotherapy; case report; cerebrospinal fluid; cervical spinal cord; feces incontinence; female; folic acid blood level; home care; hospital discharge; hospital readmission; human; limb weakness; micturition; multiple cycle treatment; neurologic disease; nuclear magnetic resonance imaging; paresthesia; recurrent disease; remission; sensory dysfunction; spinal cord disease; T cell lymphoma; unspecified side effect; urine incontinence; vitamin blood level; Adult; Antineoplastic Agents; Diagnosis, Differential; Female; Humans; Lymphoma, B-Cell; Lymphoma, Lymphoblastic; Middle Aged; Spinal Cord Diseases; Subacute Combined Degeneration
Type
journal article