Disseminated Streptococcus anginosus infection with empyema thoracis in a patient with sarcoma
Journal
Journal of the Formosan Medical Association
Journal Volume
105
Journal Issue
9
Pages
760-764
Date Issued
2006
Author(s)
Abstract
Streptococcus anginosus is a member of the normal flora of the oral cavity and a pathogen of thoracic infection. However, disseminated infection that was identified from different body fluids at the same time has never been reported. We report a 52-year-old man with advanced pulmonary sarcoma who developed neutropenia, bronchopleural fistula and thoracic empyema after chemotherapy. Viridans group Streptococcus was isolated from both empyema and urine, which was confirmed as S. anginosus according to the biochemical reaction profiles and 16S rRNA gene sequencing results. The patient recovered uneventfully after tube drainage and treatment with imipenem. Disseminated S. anginosus infection should be considered as a possible pathogen in immunocompromised patients with empyema and can be rapidly identified by 16S rRNA gene sequencing. ? 2006 Elsevier & Formosan Medical Association.
SDGs
Other Subjects
C reactive protein; cefepime; cefotaxime; etoposide; ifosfamide; imipenem; adult; anemia; article; artificial ventilation; bacterium identification; bronchopleural fistula; bronchoscopy; bronchus rupture; cancer combination chemotherapy; case report; clinical feature; computer assisted tomography; febrile neutropenia; fever; hospital infection; human; hyperammonemia; hyperbilirubinemia; hypoxia; intensive care unit; laboratory test; leukocytosis; leukopenia; lung infection; lung sarcoma; lung tumor; male; metabolic acidosis; minimum inhibitory concentration; nonhuman; nucleotide sequence; physical examination; pleura effusion; pleura empyema; pneumonia; protein blood level; respiratory failure; septic shock; Streptococcus anginosus; Streptococcus infection; surgical drainage; thoracocentesis; thorax drainage; thorax radiography; thrombocyte count; treatment duration; treatment outcome
Type
journal article