Development of novel antibacterial-modified thermoplastic polyurethane and urethane-acrylate materials for dental root canal filling
Date Issued
2015
Date
2015
Author(s)
Chiang, Tung-Jung
Abstract
Conventional root canal materials do not have enough dentinal adhesion and cannot achieve the ideal sealing properties with cone materials. Our research team have developed the polyurethane root canal obturation system containing PBA polyol-based cone materials and dual cured urethane acrylate sealer. Although these materials have good mechanical properties and bonding strength to dentin, the cytotoxicity and hydrolytic stability are questioned. The purpose of this study was to develop a novel polyurethane-based root obturation material, including cone and sealer materials. At first, we developed the low hydrolytic polyurethane cone material by replacing the PBA polyol with PTMO polyol and investigated the thermal properties. The results showed that the PTMO-based polyurethane cone material cannot be used in human body because the low melting point. Thus, cone materials was synthesized from polyester-type polyol and covalently bonded with CHX. For the sealer materials, ultraviolet-light photo polymerization urethane-acrylate oligomer was synthesized and covalently bonded with CHX to mix with dilute monomer to form UA/TPGDA resin. From FT-IR and NMR analysis, CHX have covalently bonded with matrix. TGA and DSC showed thermal properties appropriate for the clinical temperature. The consequences of the Cytotoxicity was better than ISO 10993-5 standard and antibacterial evaluation revealed that 0.6 wt% reached to a stable antibacterial effect.
Subjects
Root canal filling
Thermoplastic polyurethane
Urethane-acrylate resin
Cytotoxicity
Antibacterial effect
Type
thesis