Betel nut chewing and subclinical ischemic heart disease in diabetic patients
Journal
Cardiology Research and Practice
Journal Volume
1
Journal Issue
1
Pages
451489
Date Issued
2011
Author(s)
Abstract
Background. This study investigated the association between betel nut chewing and subclinical ischemic heart disease (IHD) in Taiwanese type 2 diabetic patients. Methods. A total of 394 male patients aging ? 45 years and without previous heart disease were studied. Among them 349 had no habit of chewing betel nut and 45 possessed the habit for ? 5 years. Subclinical IHD was diagnosed by a Minnesota-coded resting electrocardiogram and was present in 71 cases. Statistical analyses were performed considering confounding effects of age, diabetic duration, smoking, body mass index, blood pressure, dyslipidemia, and metabolic control status. Results. Betel nut chewers were younger and had higher prevalence of smoking (86.7 versus 60.5), higher body mass index, poorer glycemic control, and higher prevalence of subclinical IHD (28.9 versus 16.6). Patients with subclinical IHD were older and had higher prevalence of betel nut chewing (18.0 versus 9.9). The multivariate-adjusted odds ratio for subclinical IHD for chewers versus nonchewers was 4.640 (1.958-10.999). The adjusted odds ratios in younger or older patients divided by the median age of 63 years were similar: 4.724 (1.346-16.581) and 4.666 (1.278-17.028), respectively. Conclusions. Betel nut chewing is significantly associated with increased risk of subclinical IHD. Copyright ? 2011 Chin-Hsiao Tseng.
SDGs
Other Subjects
adult; age; article; betel nut; blood pressure; body mass; controlled study; disease association; disease duration; dyslipidemia; electrocardiogram; follow up; glycemic control; human; ischemic heart disease; major clinical study; male; non insulin dependent diabetes mellitus; prevalence; priority journal; risk factor; smoking; Taiwan
Type
journal article