巴金森病人之情緒功能:長期追蹤研究(III)
Date Issued
2003
Date
2003
Author(s)
花茂棽
DOI
912413H002008
Abstract
Parkinson’s disease (PD) is a prevailing degenerative disease of central nervous
system. Motor symptoms, cognitive impairments including dementia, and emotional
disturbances, especially depression are the cardinal features of the disease. The
prevalence rate of depression and anxiety in the parkinsonian patients has a great
variation. The present 3-year follow-up study, thus, is designed to examine emotional
function in these patients.
In this third-year study, we included a total of 192 adult participants, 127 patients
with idiopathic PD and 65 normal controls. On the basis of the motor staging of
Hoehn and Yahr (1967), Group 1 consisted of 58 patients with the staging I, Group 2
included 52 patients with the staging II, and Group 3 were composed of 18 patients
with the staging III. Each subject received a series of non-emotional
neuropsychological test battery, and emotional status measures. The significant
informant of each subject also received a series of emotional function measures. 53
patients completed the first-year follow-up. Among these, 21 of them were rated as
the staging I in terms of their motor disabilities; 17 the staging II; and 9 the staging III,
as well as 6 normal counterparts. 22 of these subjects have received the second-year
follow-up. Among them, 4 patients were rated as the staging I of Hoehn-Yahr Scale, 3
the staging II, and 5 the staging III, as well as 10 of normal control subjects.
Because of a high dropout rate, only 6 out of 12 patients completed the 2nd-year
follow-up of emotional status examination. The preliminary results revealed that
about 50% of our patients manifested depression symptom. Among them, 50% of
patients with staging I, 100% with staging II, and 33% with staging III were evident
of this symptom. About 33% suffered from Major Depressive Disorder in which 50%,
0%, and 33% with the motor stagings I-III respectively had this disorder. About 40%
of our patients suffered from the syndrome of dementia based on the demented
diagnostic criteria of the DSM-IV. However, about 50% of these demented patients
were also evident of depression problem.
Subjects
Emotional Status
Parkinson’s Disease
Monoaminergic Imbalance
Publisher
臺北市：國立臺灣大學心理學系暨研究所
Type
report
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