Validation of the EQ-5D in Patients with Traumatic Limb Injury
Journal
Journal of Occupational Rehabilitation
Journal Volume
25
Journal Issue
2
Pages
387-393
Date Issued
2015
Author(s)
Abstract
Purpose The measurement properties of the EQ-5D have not been explored for patients with traumatic limb injuries. The purpose of this study was to examine the construct validity, predictive validity, and responsiveness of the EQ-5D in patients with traumatic limb injuries. Methods A consecutive cohort of 1,167 patients was assessed with the EQ-5D and the World Health Organization Quality of Life instrument (WHOQOL-BREF) at baseline while the patients were hospitalized because of the injury, and the patients were followed up at 3?months (1,003 patients), 6?months (1,010 patients), and 12?months (987 patients) after injury via telephone interview. Results The utility and visual analogue scale (VAS) scores of the EQ-5D had moderate to high association with the physical and psychological domains and the two general questions (overall QOL and overall health) of the WHOQOL-BREF at all time points except baseline (Pearson’s correlation coefficient >0.3), but the EQ-5D profiles were weakly associated with the social and environment domains of the WHOQOL-BREF (absolute value of Spearman’s correlation coefficient <0.3). These results indicate that the EQ-5D has satisfactory construct validity. The utility and VAS scores of the EQ-5D at 3 and 6?months after injury can predict (with moderate to large relationships) the four domains and two general questions of the WHOQOL-BREF administered at 12?months after injury. The responsiveness of the utility and VAS of the EQ-5D were high (effect sizes >0.9) at 0–3, 0–6, and 0–12?months after injury. Conclusions The EQ-5D has sufficient construct validity, predictive validity, and responsiveness, and also provides evidence for using the utility of the EQ-5D for cost-utility analyses of patients with traumatic limb injuries in the future. ? 2014, Springer Science+Business Media New York.
SDGs
Other Subjects
adult; cohort analysis; female; health status indicator; human; injury scale; Leg Injuries; male; middle aged; pain measurement; predictive value; prognosis; psychology; psychometry; quality of life; Taiwan; treatment outcome; validation study; Adult; Cohort Studies; Female; Health Status Indicators; Humans; Injury Severity Score; Leg Injuries; Male; Middle Aged; Pain Measurement; Predictive Value of Tests; Prognosis; Psychometrics; Quality of Life; Taiwan; Treatment Outcome
Publisher
Springer New York LLC
Type
journal article