Radiation-induced chondrosarcoma of the external ear canal - Case report
Journal
Journal of Taiwan Otolaryngology - Head and Neck Surgery
Journal Volume
34
Journal Issue
5
Pages
436-439
Date Issued
1999
Author(s)
Abstract
Radiation therapy is the mainstay treatment for nasopharyngeal carcinoma (NPC). Nevertheless, the incidence of radiation-induced sarcoma (RIS) remains low in patients with NPC, and radiation-induced chondrosarcoma has not been reported. Herein, we report the case of a 45-year-old man who developed radiation-induced chondrosarcoma in the cartilaginous ear canal eight years after receiving radiation therapy for an NPC. On admission, he complained of tenderness and swelling in the left ear canal. Physical examination revealed a smooth bulging mass originating from the cartilaginous ear canal. Lateral temporal bone resection was performed and pathological examination revealed chondrosarcoma. The post-operative course was smooth and no evidence of tumor recurrence was found during the follow-up of 8 months. The location of the tumor, the interval after previous irradiation, and the histological findings were all consistent with a diagnosis of RIS. To our knowledge, this is the first reported case of radiation-induced chondrosarcoma. Because early diagnosis of RIS offers the only chance for cure, early work-up of any fresh pain and swelling in an irradiated field is vital.
Subjects
Chondrosarcoma; External ear canal; Nasopharyngeal carcinoma; Radiation-induced sarcoma
SDGs
Other Subjects
adult; article; bone resection; cancer radiotherapy; case report; chondrosarcoma; early diagnosis; external auditory canal; human; male; nasopharynx carcinoma; postoperative period; tumor recurrence
Type
journal article