Toward the Syntheses of Molecular Receptors for Catechol-Related Neurotransmitters
Date Issued
2004
Date
2004
Author(s)
Shih, Chih-Wen
DOI
zh-TW
Abstract
Some catechol-related compounds such as dopamine and norepinephrine are reported to be very important neurotransmitters. It is well known that schizophrenia, melancholia and Parkinson's disease all related the abnormally releasing of these neurotransmitters in brain. Since the molecular clips composed by diphenylglycoluril units are reported to be good catechol binders. We plan to build new molecular clips by linking diphenylglycoluril motif with crown ethers and use them as receptor molecules to detect dopamine-related neurotransmitters.
Subjects
神經傳導物質
鄰苯二酚
多巴胺
catechol
dopamine
neurotransmitter
Type
thesis
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