Upregulation of C/EBPα Inhibits Suppressive Activity of Myeloid Cells and Potentiates Antitumor Response in Mice and Patients with Cancer
Journal
Clinical cancer research : an official journal of the American Association for Cancer Research
Journal Volume
27
Journal Issue
21
Date Issued
2021-11-01
Author(s)
Hashimoto, Ayumi
Sarker, Debashis
Reebye, Vikash
Jarvis, Sheba
Sodergren, Mikael H
Kossenkov, Andrew
Sanseviero, Emilio
Raulf, Nina
Vasara, Jenni
Andrikakou, Pinelopi
Meyer, Tim
...etc.
Abstract
To evaluate the mechanisms of how therapeutic upregulation of the transcription factor, CCAAT/enhancer-binding protein alpha (C/EBPα), prevents tumor progression in patients with advanced hepatocellular carcinoma (HCC) and in different mouse tumor models.
SDGs
Type
journal article