In vitro susceptibilities of isolates of potentially naturally inducible chromosomal AmpC-producing metallo-β-lactamase-negative carbapenem-resistant Enterobacterales species to ceftazidime-avibactam: Data from the Antimicrobial Testing Leadership and Surveillance Programme, 2012-2019
Journal
International journal of antimicrobial agents
Journal Volume
60
Journal Issue
3
Date Issued
2022-09
Author(s)
Abstract
A total of 74 570 potentially naturally inducible chromosomal AmpC-producing (PNIC-AmpC) Enterobacterales isolates included in the Antimicrobial Testing Leadership and Surveillance Programme were obtained worldwide during 2012-2019 (22 503 from 2012-2014 and 52 067 from 2015-2019). Of these isolates, 117 and 711 obtained during 2012-2014 and 2015-2019, respectively, were carbapenem-resistant Enterobacterales (PNIC-AmpC-CRE). The MICs of ceftazidime-avibactam for these isolates were determined using the broth microdilution method.
Subjects
Carbapenem-resistant Enterobacterales; Ceftazidime-avibactam; Metallo-β-lactamase; Potentially naturally inducible chromosomal (PNIC) AmpC-producers; Resistance
SDGs
Type
journal article