ATP8B1: A prognostic prostate cancer biomarker identified via genetic analysis
Journal
The Prostate
Journal Volume
83
Journal Issue
6
Date Issued
2023-05
Author(s)
Chen, Lih-Chyang
Huang, Shu-Pin
Shih, Chieh-Tien
Li, Chia-Yang
Chen, Yei-Tsung
Yu, Chia-Cheng
Lin, Victor C
Lee, Cheng-Hsueh
Geng, Jiun-Hung
Bao, Bo-Ying
Abstract
Controlling the asymmetric distribution of phospholipids across biological membranes plays a pivotal role in the life cycle of cells; one of the most important contributors that maintain this lipid asymmetry are phospholipid-transporting adenosine triphosphatases (ATPases). Although sufficient information regarding their association with cancer exists, there is limited evidence linking the genetic variants of phospholipid-transporting ATPase family genes to prostate cancer in humans.
Subjects
ATP8B1; androgen-deprivation therapy; biomarker; prostate cancer; survival
SDGs
Type
journal article