Multiphoton fluorescence and second harmonic generation microscopy of different skin states
Journal
Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Journal Volume
5686
Date Issued
2005-08-16
Author(s)
Abstract
In recent years, non-linear imaging techniques such as multiphoton fluorescence and harmonic generation microscopy have been successfully applied to dermatological imaging. Confocal-like image quality, enhanced depth penetration, and non-linear spectral signatures are among the main advantages of this family of techniques. In this presentation, we will focus on the applications of multiphoton microscopy to skin specimens in different physiological states. Images of normal and diseased tissue specimens will be presented and spectrally characterized. Our work has potential applications in developing multiphoton microscopy into a clinically applicable diagnostic tool.
Subjects
Multiphoton fluorescence microscopy | Second-harmonic generation | Skin imaging
Type
conference paper