Plasmapheresis in acute disseminated encephalomyelitis
Journal
Journal of Clinical Apheresis
Journal Volume
19
Journal Issue
3
Pages
154-159
Date Issued
2004
Author(s)
Abstract
High-dose corticosteroid administration has been regarded as the main therapy for acute disseminated encephalomyelitis (ADEM). However, some patients with ADEM do not respond well to this treatment. We successfully used plasmapheresis to treat 2 patients who had ADEM. We also compared our patients' symptoms and clinical outcomes to those from previous reports. Plasmapheresis may be indicated not only for severe cases that fail to improve after high-dose corticosteroid treatment but also for first-line treatment. Additional large, controlled, double-blinded trials are needed to clarify the role of plasmapheresis in ADEM. ? 2004 Wiley-Liss, Inc.
SDGs
Other Subjects
immunoglobulin; levamisole; methylprednisolone; prednisolone; rubella vaccine; acute disease; adult; aged; article; ataxia; case report; clinical feature; diagnostic imaging; drug megadose; drug response; dysphagia; encephalomyelitis; female; follow up; human; hyperreflexia; lethargy; lichen planus; muscle weakness; myoclonus; nuclear magnetic resonance imaging; plasmapheresis; postinfection encephalitis; quadriplegia; symptom; treatment failure; treatment indication; Adrenal Cortex Hormones; Adult; Aged; Encephalomyelitis, Acute Disseminated; Female; Humans; Immunoglobulins, Intravenous; Plasmapheresis
Type
journal article