Simultaneous En-bloc Kidney and Pancreas Transplantation (SEBKP) from Pediatric Donors: Selection, Surgical Strategy, Management and Outcomes.
Journal
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
ISSN
1600-6143
Date Issued
2024-11-18
Author(s)
Tamburrini, Riccardo
Philip, Jennifer L
Neidlinger, Nikole A
Kaufman, Dixon B
Odorico, Jon S
Abstract
Pediatric donors are underutilized for simultaneous pancreas-kidney transplantation (SPK) due to concern about technical complications and inadequate islet and/or renal mass. We analyzed our experience with simultaneous en-bloc kidney and pancreas transplantation (SEBKP) using pediatric donors on eight consecutive adult patients from 1997-2018. En-bloc kidney transplants were implanted intraperitoneally and contralaterally to right-sided pancreas grafts. All patients became insulin independent immediately; with one case of delayed kidney function and one case of insulin resistance; there were no graft thromboses. Donor age averaged 5.0±1.7 years and weight 19.8±4.8kg; recipients averaged 46.6±12.8 years and BMI 25.2±3.8kg/m. Postoperative creatinine, glucose and c-peptide reflected good graft function. SEBKP transplantation is a safe technique providing excellent long-term glycemic control and kidney function to adult recipients.
Subjects
Extended Criteria
Simultaneous En-bloc Kidney and Pancreas Transplantation
pancreas transplantation
pediatric donation
simultaneous kidney and pancreas transplant
SDGs
Type
journal article