Metallic ureteral stents in malignant ureteral obstruction: Clinical factors predicting stent failure
Journal
Journal of Endourology
Journal Volume
28
Journal Issue
6
Pages
729-734
Date Issued
2014
Author(s)
Abstract
Purpose: To provide clinical outcomes of the Resonance metallic ureteral stent in patients with malignant ureteral obstruction, as well as clinical factors predicting stent failure. Methods: Cancer patients who have received Resonance stents from July 2009 to March 2012 for ureteral obstruction were included for chart review. Stent failure was detected by clinical symptoms, image studies, and renal function tests. Survival analysis for stent duration was used to estimate patency rate and factors predicting stent failure. Results: A total of 117 stents were inserted successfully into 94 ureteral units in 79 patients. There were no major complications. These stents underwent survival analysis and proportional hazard regression. The median duration for the stents was 5.77 months. In multivariate analysis, age (P=0.043), preoperative serum creatinine level (P=0.0174), and cancer type (P=0.0494) were significant factors associated with stent failure. Cancer treatment before and after stent insertion had no effect on stent duration. Conclusions: Resonance stents are effective and safe in relieving malignant ureteral obstructions. Old age and high serum creatinine level are predictors for stent failure. Stents in patients with lower gastrointestinal cancers have longer functional duration. ? 2014 Mary Ann Liebert, Inc.
SDGs
Other Subjects
creatinine; adult; aged; anus cancer; appendix cancer; article; bladder cancer; breast cancer; colon cancer; colorectal cancer; creatinine blood level; dysuria; female; flank pain; follow up; hematuria; human; kidney function test; lung cancer; lymphoma; major clinical study; male; malignant ureteral obstruction; medical device complication; medical record review; metal stent; metallic ureteral stent; multivariate analysis; outcome assessment; ovary cancer; pancreas cancer; priority journal; prostate cancer; rectum cancer; retrospective study; sarcoma; small intestine cancer; stent migration; stomach cancer; survival; treatment duration; treatment failure; ureter obstruction; ureter stent; urinary frequency; urinary tract infection; uterine cervix cancer; very elderly; Adult; Age Factors; Aged; Aged, 80 and over; Biological Markers; Creatinine; Equipment Failure Analysis; Female; Humans; Male; Middle Aged; Multivariate Analysis; Neoplasms; Predictive Value of Tests; Proportional Hazards Models; Retrospective Studies; Stents; Time Factors; Ureteral Obstruction
Type
journal article