Study of photon migration with various sourcedetector separations in near-infrared spectroscopic brain imaging based on threedimensional monte carlo modeling
Journal
Optics Express
Journal Volume
13
Journal Issue
21
Pages
8339-8348
Date Issued
2005
Author(s)
Lee C.-K.
Sun C.-W.
Lee P.-L.
Jiang C.-P.
Tong Y.-P.
Yeh T.-C.
Hsieh J.-C.
Lee C.-K.
Sun C.-W.
Lee P.-L.
Yang C.C.
Jiang C.-P.
Tong Y.-P.
Yeh T.-C.
Abstract
We have simulated the photon migration with various sourcedetector separations based on a three-dimensional Monte Carlo code. The whole brain MRI structure images are introduced in the simulation, and the brain model is more accurate then the previous studies. The brain model consists of scalp, skull, CSF layer, gray matter, and white matter. We demonstrate dynamic propagating movies under different source-detector separations. The multiple backscattered intensity from every layer of the brain model is obtained by marking the deepest layer which every photon can reach. Also the influences of an absorption target on brain cortex are revealed. © 2005 Optical Society of America.
Other Subjects
Absorption; Brain; Computer simulation; Infrared spectroscopy; Magnetic resonance imaging; Mathematical models; Gray matter; Monte Carlo code; Photon migration; Photons
Type
journal article