Method for Testing for Human Papillomavirus Infection in Patients with Cervical Intraepithelial Disease
Journal
Journal of Clinical Microbiology
Journal Volume
42
Journal Issue
1
Pages
366-368
Date Issued
2004
Author(s)
Abstract
To determine whether DNA detection of high-risk human papillomavirus could represent a reliable screening technique and a useful follow-up method, we investigated the performance of the Hybrid Capture II assay in detecting high-grade cervical lesions. The test positivity at 1.86 pg/ml had a high sensitivity (94.7%) and improved specificity. It was also a suitable follow-up method for detecting the recurrence of cervical intraepithelial disease in patients.
SDGs
Other Subjects
virus DNA; adult; aged; analytic method; article; controlled study; diagnostic value; disease severity; DNA determination; female; follow up; high risk population; human; infection risk; major clinical study; Papilloma virus; priority journal; recurrent disease; reliability; screening test; sensitivity and specificity; uterine cervix disease; uterine cervix epithelium; virus infection; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; DNA, Viral; Female; Humans; Middle Aged; Papillomaviridae; Papillomavirus Infections; Uterine Cervical Diseases; DNA viruses; Human papillomavirus; Papillomavirus
Type
journal article