Ocular surface microbiota: Ophthalmic infectious disease and probiotics
Journal
Frontiers in microbiology
Journal Volume
13
Pages
952473
Date Issued
2022-08-19
Author(s)
Chiang, Ming-Cheng
Abstract
Recently, increasing studies have emphasized the importance of commensal bacteria in humans, including microbiota in the oral cavity, gut, vagina, or skin. Ocular surface microbiota (OSM) is gaining great importance as new methodologies for bacteria DNA sequencing have been published. This review outlines the current understanding and investigation of OSM and introduces the new concept of the gut-eye axis. Moreover, we have collected current studies that focus on the relationship between ophthalmic infectious disease and alterations in the OSM or human gut microbiota. Finally, we discuss the current application of probiotics in ophthalmic infectious disease, its limitations to date, and futural directions.
Subjects
gut–eye axis; microbiome; ocular surface microbiota; ophthalmic infectious disease; probiotic
SDGs
Publisher
FRONTIERS MEDIA SA
Type
review