Increase in B19 Viral Load Prior to Relapse of Anaemia in an Aids Patient with Persistent B19 Infection
Resource
JOURNAL OF INFECTION v.43 n.2 pp.150-152
Journal
JOURNAL OF INFECTION
Journal Volume
v.43
Journal Issue
n.2
Pages
150-152
Date Issued
2001
Date
2001
Author(s)
CHEN, MAO-YUAN
Abstract
Anaemia caused by persistent parvovirus B19 infection can be remitted by intravenous immunoglobulin (IVIG) treatment. However. maintenance IVIG therapy is required in some AIDS patients as well as patients with combined immunodeficiency because of relapse of anaemia. We used a simple semi- quantitative polymerase chain reaction (PCR) method to trace plasma B19 viral load after administration of IVIG. We noted that the rebound of B19 viral load occurred 6 weeks prior to detection of anaemia. This method may be helpful in determining the interval of maintenance IVIG therapy. ( C) 2001 The British Infection Society.
Subjects
RED-CELL APLASIA
PARVOVIRUS B19
IMMUNODEFICIENCY
IMMUNOGLOBULIN
DURATION
THERAPY
SDGs
Type
journal article