Synthesis, Characterization, and Application of Nanostructured Silica Materials
Date Issued
2004
Date
2004
Author(s)
Lin, Yu-Shen
DOI
en-US
Abstract
My research goal is exploring new properties for silica based materials. In this thesis, the topics are divided into four sections: (i) lanthanide incorporated nanosized mesoporous silica and the potential as MRI contrast agent, (ii) synthesis and characterization of lanthanide hydroxide@silica colloidal sphere, (iii) well-ordered mesoporous nanoparticle and the potential in biological application, and (iv) simple synthesis of well-ordered super-microporous aluminosilicate.
In the first part, we have successfully synthesized Ln(III) incorporated mesoporous silica nanoparticels (Ln-MS) by acid-to-base and high dilution method. In addition to the inherent properties of mesoporous silica, the Gd-MS porous silica exhibits an additional ability on the enhancement of water proton relaxation. We believe these materials may be useful in biological tracking and imaging applications. In the second part, we have synthesized monodisperse lanthanide hydroxide@silica core sphere in base condition. The monodisperse core-shell spheres are promising to serve as building blocks to fabricate photonic crystals for further optical investigations. In the third part, we have demonstrated for the first time that the mesoporous silica nanoparticles can translocate into cell and have no short term toxicity on the cell; hence, open up an exciting field of mesoporous silica in biomedical applications. In the fourth part, we have provided a simple method for the synthesis of highly ordered super-microporous aluminosilicates by using co-surfactant system. We expect the materials to be useful in catalysis and gas adsorption studies. All in all, we have demonstrated the great potential of mesoporous and spherical silica nanoparticles in the exciting biomedical field.
Subjects
氧化矽
磁照影
光晶
Silica
MRI
Photonics
Type
thesis
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