Diffuse Optical Tomography: Optode Design and Clinical Study
Date Issued
2007
Date
2007
Author(s)
Wu, Chun-Ming
DOI
zh-TW
Abstract
Diffuse optical tomography (DOT) is the technique that probes and images spatial variations in absorption and scattering properties of the biological tissues. DOT can accurately measure simultaneous changes in concentrations of oxy-hemoglobin and deoxy-hemoglobin. The oxygenation images have been reconstructed by the measured hemodynamics signals with nearest-neighbor pairs of sources and detectors. In our study, a portable DOT system is built with optode design on flexible print circuit board (PCB). The DAQ card is used to PC connection for multiplex driving of laser diodes and detected signal process form photodiodes on optode in DOT system.
In this thesis, the principles and systematic designs of DOT are demonstrated. In experiments, the excise and vessel occlusion hemodynamics are observed with in vivo measurements form normal subjects and some patients in intensive care unit.
Subjects
擴散光學斷層掃瞄術
近紅外光光譜學
醫學造影
造影系統
Diffuse optical tomography
Near-infrared spectroscopy
Medical imaging
Imaging system
Type
thesis
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