3d-printed collagen-based waveform microfibrous scaffold for periodontal ligament reconstruction
Journal
International Journal of Molecular Sciences
Journal Volume
22
Journal Issue
14
Pages
7725
Date Issued
2021
Author(s)
Abstract
shear stress, PDL cells were successfully seeded, and cytoskeleton expansion, adhesion, and viability were greater. Cyclin D, E-cadherin, and periostin were upregulated on the waveform microfibers. In conclusion, 3D-printed collagen-based waveform microfibers preserved PDL cell viability and exhibited an enhanced tendency to promote healing and regeneration under shear stress. This approach is promising for the development of a guiding scaffold for PDL regeneration.
Publisher
MDPI
Type
journal article