Selective Deprotection of Acetals with Me3SiCH2MgCl. Peterson-Type Olefination of Acetals
Resource
Journal of Organic Chemistry 65 (15): 4694-4697
Journal
Journal of Organic Chemistry
Journal Volume
65
Journal Issue
15
Pages
4694-4697
Date Issued
2000
Date
2000
Author(s)
Abstract
By employing the chelation strategy, treatment of an acetal of a contiguous diol with Me3SiCH2MgCl liberates the corresponding diol regioselectively. In addition, acetals of different structural variety are transformed upon treatment with Me3SiCH2MgCl and ZnI2 into the corresponding olefination products in good yield.
Type
journal article
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